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Apr

Exploring gene mutations with Oncogenomics Explorer – mutation types to function to co-occurrence

Acute myeloid leukemia (AML) is the most common acute leukemia among adults. Mutations in DNA (cytosine-5)-methyltransferase 3A (DNMT3A) has been linked to poor survival of AML patients1. Identification of DNMT3A and other co-occurring mutations might be a useful marker in patient prognosis but also in stratification of patients for targeted therapeutics. The question: How to search for DNMT3A...
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